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Sister Winifred takes up dental hygiene while Trixie deals with a patient who's terrified of the dentist. After a vulnerable young man with Down syndrome endures a tragedy, Fred and Violet struggle to help him and find him a new home.

Frances tries to erase Peter's affair from her life, the Campbells receive some good news but Dr. Campbell delivers an upsetting diagnosis to the Brindsleys, Laura finds a new occupation, Pat's affair reaches a crisis, and Teresa goes on a date.

Numerous mothers contend with the loss of a child in various forms, while Shelagh's pregnancy comes to a crisis. The Nonnatans search for a new midwife, Dr. Turner and his son's relationship deepens, and a "chariot race" enlivens Poplar.

Frances learns some shocking details about Peter's affair, Pat's affair encounters difficulty, and Sarah is warned of being too fond of a certain man. Slander and vandalism rattle Joyce and Alison faces an ethical quandary. 

Sister Ursula may seem to be a villain. But she soon changes her tune after being rocked by a near-tragedy. Mrs. Chen is also difficult, but her past provides a motive for her behavior towards her daughter-in-law and her newborn.

Tensions increase as Laura's affair becomes public, Frances mourns her husband and deals with a strange codicil to his will, Dr. Campbell begins chemotherapy, and Joyce Cameron returns. 

Big problems threaten the birth of a healthy child for Penny Reed, but Patsy offers her full support. In the wake of a tragedy at the docks, Shelagh attempts in a small way to ensure safer working conditions, especially after seeing the devastation the accident wreaks on the Marsh family.

A long-time Italian resident of Great Paxford and a regiment of Czech soldiers incite tension and cruel behavior. Meanwhile, unfortunate or non-existent news about men of the town who have gone off to war doesn't help ease people's nerves.

In the first episode of Call the Midwife's sixth season, there have been some unpleasant changes at Nonnatus House. Sister Mary Cynthia deals with lingering trauma, the patient of the week undergoes her own traumatic experiences, and some of the Nonnatus staff hit major life landmarks.

As Victoria enters the final weeks of her pregnancy and Victoria the final episode of its first season, the Queen feels cooped up and stifled. What dangers lurk on the streets of London -- or worse, amongst Victoria's own family? 

In the wake of the Battle of Antietam and the Emancipation Proclamation, the lives of the characters of Mercy Street change drastically in this finale, as some undertake journeys and some decide to stay put.

The palace is embracing change, as Victoria copes with a pregnancy, Albert and Sir Peel tout locomotives, and Francatelli and Skerrett innovate in the kitchen.

Some people exploit the suffering of the war for their own advantage, while others strive only to alleviate pain and end the conflict. Where do the denizens of Alexandria fall?

Folk contraceptive methods, forbidden romances, an outbreak of plague, squabbles over court hierarchy, noble oration: this episode's got it all. 

Being a decent person in this war is dangerous. Being a woman just adds to the difficulty, but the women of Alexandria don't let that stop them from helping their side.